LymphedemaV1, Main, Exploration, bibRecord, 00D020

Reduction of filaritic lymphoedema and elephantiasis by 5,6 benzo-a-pyrone (coumarin), and the effects of diethylcarbamazine (DEC)

Identifieur interne : 00D020 ( Main/Exploration ); précédent : 00D019; suivant : 00D021

Reduction of filaritic lymphoedema and elephantiasis by 5,6 benzo-a-pyrone (coumarin), and the effects of diethylcarbamazine (DEC)

Auteurs : J. R. Casley-Smith [Australie] ; S. Jamal ; J. R. Casley-Smith

Source :

Annals of tropical medicine and parasitology [ 0003-4983 ] ; 1993.

RBID : Pascal:93-0640187

Descripteurs français

KwdFr :
- Adulte, Adulte d'âge moyen, Association de médicaments, Coumarines (usage thérapeutique), Diéthylcarbamazine (usage thérapeutique), Femelle, Filariose lymphatique (traitement médicamenteux), Humains, Lymphoedème (traitement médicamenteux), Mâle, Méthode en double aveugle, Sujet âgé.
MESH :
- traitement médicamenteux : Filariose lymphatique, Lymphoedème.
- usage thérapeutique : Coumarines, Diéthylcarbamazine.
Pascal (Inist)
- Adulte, Adulte d'âge moyen, Association de médicaments, Femelle, Humains, Lymphoedème, Eléphantiasis, Diéthylcarbamazine, Filariose, Mâle, Méthode en double aveugle, Sujet âgé, Système lymphatique, Antiparasitaire, Anthelminthique, Inde, Coumarine dérivé, Homme.
Wicri :
- geographic : Inde.
- topic : Homme.

English descriptors

KwdEn :
- Adult, Aged, Anthelmintic, Coumarine derivatives, Coumarins (therapeutic use), Diethylcarbamazine (therapeutic use), Double-Blind Method, Drug Therapy, Combination, Elephantiasis, Elephantiasis, Filarial (drug therapy), Female, Filariosis, Human, Humans, India, Lymphatic system, Lymphedema, Lymphedema (drug therapy), Male, Middle Aged, Parasiticid.
MESH :
- chemical , therapeutic use : Coumarins, Diethylcarbamazine.
- drug therapy : Elephantiasis, Filarial, Lymphedema.
- Adult, Aged, Double-Blind Method, Drug Therapy, Combination, Female, Humans, Male, Middle Aged.

Abstract

Chronic filaritic lymphoedema and elephantiasis, in India, were treated orally with 5,6 benzo-a-pyrone (56 BaP; 1,2 benzo-a-pyrone; coumarin) in a double-blind, randomized, matched-group trial. Each group finally contained 40-55 patients. Patients were observed for about 2 years (ranging from 6 to 45 months, with 75% completing the 2 years). The 56 BaP slowly, but very significantly (P < 0.0001), reduced all grades of lymphoedema and elephantiasis. Two thirds of the oedema was lost by grade 2 over 2 years. Grades 3 to 5 were reduced by a fifth over that time. The greater the initial oedema, the greater was its rate of resolution

Affiliations:

Australie

Le document en format XML

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<term>Anthelmintic</term>
<term>Coumarine derivatives</term>
<term>Coumarins (therapeutic use)</term>
<term>Diethylcarbamazine (therapeutic use)</term>
<term>Double-Blind Method</term>
<term>Drug Therapy, Combination</term>
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<term>Lymphatic system</term>
<term>Lymphedema</term>
<term>Lymphedema (drug therapy)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Parasiticid</term>
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<term>Coumarines (usage thérapeutique)</term>
<term>Diéthylcarbamazine (usage thérapeutique)</term>
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<term>Méthode en double aveugle</term>
<term>Sujet âgé</term>
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<term>Lymphoedème</term>
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<term>Diéthylcarbamazine</term>
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<term>Double-Blind Method</term>
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<term>Humans</term>
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<term>Lymphoedème</term>
<term>Eléphantiasis</term>
<term>Diéthylcarbamazine</term>
<term>Filariose</term>
<term>Mâle</term>
<term>Méthode en double aveugle</term>
<term>Sujet âgé</term>
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<term>Antiparasitaire</term>
<term>Anthelminthique</term>
<term>Inde</term>
<term>Coumarine dérivé</term>
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<front><div type="abstract" xml:lang="en">Chronic filaritic lymphoedema and elephantiasis, in India, were treated orally with 5,6 benzo-a-pyrone (56 BaP; 1,2 benzo-a-pyrone; coumarin) in a double-blind, randomized, matched-group trial. Each group finally contained 40-55 patients. Patients were observed for about 2 years (ranging from 6 to 45 months, with 75% completing the 2 years). The 56 BaP slowly, but very significantly (P < 0.0001), reduced all grades of lymphoedema and elephantiasis. Two thirds of the oedema was lost by grade 2 over 2 years. Grades 3 to 5 were reduced by a fifth over that time. The greater the initial oedema, the greater was its rate of resolution</div>
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Reduction of filaritic lymphoedema and elephantiasis by 5,6 benzo-a-pyrone (coumarin), and the effects of diethylcarbamazine (DEC)

Reduction of filaritic lymphoedema and elephantiasis by 5,6 benzo-a-pyrone (coumarin), and the effects of diethylcarbamazine (DEC)

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

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